Greenlight Laser for BPH – A Prospective international study on indications and outcomes
During the past two decades we are witnessing the incorporation of an increasing number minimal invasive treatments for Benign Prostatic Hyperplasia. Laser treatment is truly on the rise, most probably due to technical refinements of the technology and refinement of endoscopic equipment.
There are some fundamental (institutional) differences, however, concerning indication for surgery, experience, technique used and maybe outcomes. Moreover specific factors may influence treatment related morbidity. In this prospective study we will study on a global base the indications and outcomes of HPS greenlight laser treatment for BPH. Each centre participating in this project will include during a one-year period the patients treated at their site.
Download the HPS protocol

Primary study objective:
To assess the current indications for HPS greenlight laser treatment and the treatment outcomes in terms of objective and subjective improvement
Secondary study objectives:
To assess the peri-operative morbidity (30 days) by using the Clavien system.
To define risk factors for the development of peri-operative morbidity after HPS greenlight laser treatment.
The following variables will be included to correlate in a logistic regression and uni/multivariate analysis:
The use of antibiotics and incidence of infections.
Possible differences in morbidity.
Specific medical conditions (age, BMI, DM, anticoagulants, CVD) versus outcome and morbidity
Outcomes in complicated cases (coumadine use, large prostates, etc)
To define the learning curve
To study differences between lower and higher volume sites
MANUSCRIPTS PUBLISHED/IN PREPARATION
1) The Clinical Research Office of the Endourological Society (CROES) Global GreenLight™ Laser Study: Outcomes from a contemporary series of 713 patients
Jean JMCH de la Rosette, Mostafa Elhilali, Seiji Naito, Dogan Unal, Hassan Razvi, Evangelos Liatsikos, Alexander Bachmann, Andrea Tubaro, Gerasimos Alivizatos, Siu-King Mak, Gopal Badlani, Ehab Eltahawy, Carson Wong, Martin Telich Vidal, Alexis Te, Frank CH d’Ancona, Carl Jorgen Arum, Jorge Gutierrez on behalf of the CROES GreenLight Laser Study Group
Published International Journal of Urology 2015 Dec;22(12):1124-30
2) Comparison of GreenLight laser and TURP baseline characteristics and outcomes: lessons learned from the CROES GreenLight Laser Study
Gordon Muir, Jiri Klecka,Daniel J Culkin, Gabriel H Barusso, Jan Kums, Claus R Brunken,Gregg Eure, Carlos Rioja Sanz, Fernando Gomez Sancha, Muharrem M. Yildiz, Jean JMCH de la Rosette, on behalf of the CROES GLS Study Group
In press Minerva Urol Nefrol 2016 Oct 5. [Epub ahead of print]